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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACO1
All Species:
46.97
Human Site:
T836
Identified Species:
73.81
UniProt:
P21399
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21399
NP_002188.1
889
98399
T836
L
T
G
Q
E
R
Y
T
I
I
I
P
E
N
L
Chimpanzee
Pan troglodytes
XP_001155934
889
98362
T836
L
T
G
Q
E
R
Y
T
I
I
I
P
E
N
L
Rhesus Macaque
Macaca mulatta
XP_001103675
889
98487
T836
L
T
G
Q
E
R
Y
T
I
I
I
P
E
N
L
Dog
Lupus familis
XP_538698
889
98299
T836
L
T
G
R
E
R
Y
T
I
I
I
P
D
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P28271
889
98160
T836
L
T
G
R
E
R
Y
T
I
N
I
P
E
D
L
Rat
Rattus norvegicus
Q63270
889
98109
T836
L
T
G
R
E
R
Y
T
I
H
I
P
E
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509375
889
98624
T836
L
S
G
R
E
R
Y
T
I
I
I
P
E
N
L
Chicken
Gallus gallus
Q90875
889
98055
T836
L
T
G
R
E
R
Y
T
I
I
I
P
E
N
L
Frog
Xenopus laevis
Q6NTP2
955
104418
S903
L
S
G
K
E
Q
Y
S
L
S
L
P
V
D
L
Zebra Danio
Brachydanio rerio
NP_001030155
890
98920
T836
L
S
G
R
E
R
Y
T
V
M
I
P
P
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524303
899
98560
N846
L
T
G
R
E
V
Y
N
I
A
L
P
E
S
G
Honey Bee
Apis mellifera
XP_392993
890
98796
D838
L
T
G
Y
E
V
Y
D
I
S
I
S
E
N
C
Nematode Worm
Caenorhab. elegans
Q23500
887
96642
S834
L
T
G
K
E
Q
F
S
I
G
V
P
D
D
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SIB9
990
108183
T933
L
T
G
H
E
R
Y
T
I
H
L
P
T
D
I
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
L724
P
D
D
R
I
D
I
L
G
L
A
E
L
A
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.9
93.2
N.A.
93.4
92.9
N.A.
90.4
87.5
55.7
82.2
N.A.
67.9
69.4
62.9
N.A.
Protein Similarity:
100
100
99.5
96.9
N.A.
97.7
97.7
N.A.
95.1
93.8
72.2
92
N.A.
82.1
82.5
77.1
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
86.6
93.3
40
60
N.A.
53.3
60
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
86.6
86.6
N.A.
73.3
60
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.6
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.6
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
7
7
0
0
7
0
7
0
0
0
0
14
27
0
% D
% Glu:
0
0
0
0
94
0
0
0
0
0
0
7
60
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
94
0
0
0
0
0
7
7
0
0
0
0
7
% G
% His:
0
0
0
7
0
0
0
0
0
14
0
0
0
7
0
% H
% Ile:
0
0
0
0
7
0
7
0
80
40
67
0
0
0
7
% I
% Lys:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
94
0
0
0
0
0
0
7
7
7
20
0
7
7
74
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
7
0
0
0
47
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
0
0
87
7
0
7
% P
% Gln:
0
0
0
20
0
14
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
54
0
67
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
0
0
0
0
0
14
0
14
0
7
0
7
0
% S
% Thr:
0
74
0
0
0
0
0
67
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
0
14
0
0
7
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
87
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _